# Organs of the cardiovascular diseases #
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## What is high blood pressure ##
Kasabay nito, hindi inirerekomenda ang pangmatagalang pag-inom ng mga gamot mula sa kategoryang Diuretics, dahil ang mahahalagang sangkap tulad ng Potassium, Calcium, Magnesium ay mabilis na nailalabas sa katawan kasama ng sobrang tubig at asin. Alinsunod sa katangiang ito, sinasabayan ng mga Diuretics ang pag-inom ng mga gamot na may laman ng mga sangkap na ito. Maaaring ito ay mga vitamin at mineral na complexes, monokomponent, o mga suplemento sa pagkain na may napatunayang klinikal na bisa. Of course! Here is a scientific Text on the subject is What is hypertension?:
What is hypertension?
High blood pressure, known medically as hypertension, is a chronic disease of the cardiovascular system, the blood pressure in the arteries is permanently increased. This condition is one of the most common health problems worldwide and is considered one of the most important risk factors for cardiovascular disease, including heart attack, stroke and kidney failure.
Blood pressure is expressed in two values: the systolic and the diastolic pressure. The systolic value (first value) is the pressure during the heart contraction in the vessels; the diastolic value (second value) describes blows the resting pressure between two of the heart. According to the recommendations of the German hypertension League, the following applies:
Normal value: under 130/85 mmHg;
increased atmospheric pressure: 130-139/85-89 mmHg;
High blood pressure (hypertension): from 140/90 mmHg.
There are two main forms of hypertension:
Primary (essential) hypertension: This Form accounts for the majority of cases (approximately 90-95 %) and has no single, known cause. Instead, several risk factors, including:
genetic predisposition;
Overweight and obesity;
unhealthy diet (high salt consumption);
lack of physical activity;
chronic Stress;
Alcohol and nicotine consumption.
Secondary hypertension: it arises as a Symptom of another disease, such as:
Kidney disease;
Hormonal disorders (e.g., hyperthyroidism or Cushing's syndrome);
certain medications (e.g., corticosteroids, NSAIDs);
Damage to large arteries (e.g. aortic coarctation).
Without adequate treatment of high blood pressure can lead to long-term damage. These include:
Vascular changes and atherosclerosis;
Left heart enlargement and congestive heart failure;
Damage to the kidneys (renal sclerotic renal failure);
Impairment of vision due to retinal changes.
The diagnosis of hypertension is made by the blood of repeated pressure measurements, ideally in the context of a 24‑hour blood pressure monitor (Ambulatory Blood Pressure Monitoring, ABPM). Additional investigations such as laboratory tests, ECG and ultrasound are used to determine organ investments and possible causes.
The therapy consists of lifestyle measures and pharmacological options:
Reduction of salt in the diet;
Weight reduction in Overweight;
regular physical activity;
Waiver of Smoking and reduction of alcohol consumption;
Medications such as ACE‑inhibitors, AT1‑receptor blockers, beta-blockers, calcium antagonists, or diuretics.
In conclusion, hypertension is a common, often asymptomatic, but severe disease. Early diagnosis and consequent treatment are important to prevent cardiovascular complications and to preserve the quality of life of those Affected in the long term.
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Ang presyon ng dugo ay isa sa mga pangunahing indikasyon ng kalusugan, na hindi lamang sumasalamin sa puso at sistema ng sirkulasyon, kundi pati na rin sa aktibidad ng mga bato, mga organo ng endokrin, paggawa ng dugo, at ng sistema ng nerbiyos. Kaya naman, walang isang unibersal na gamot laban sa mataas na presyon ng dugo. Hindi ka basta basta puwedeng pumunta sa botika at magtanong ng 'tableta para sa presyon,' kasi agad na tatanungin ng parmasyutiko – anong gamot ang nireseta sa iyo ng doktor?
> Kung nagsimula na ang pag-inom ng gamot para sa mataas na presyon, hindi ibig sabihin na hindi na maaaring gawin ang karagdagang mga hakbang para palakasin ang katawan sa programa ng therapy. Ang benepisyo ng maingat na mga hakbang na pinagkasunduan ng doktor ay nakakatulong para mapigilan ang paglala ng sakit at maiwasang lumipat ito sa mas seryosong yugto.

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Organs in cardiovascular disease: Pathophysiological interactions
The cardiovascular system is a complex network that includes non-vessels, the heart and the blood, but also a close relationship to other organs has. In the case of cardiovascular diseases (HKK) are often affected multiple organ systems, since the maintenance of hemodynamics requires a coordinated function of the various structures.
The heart as the Central Organ
The heart takes over as the Central driving point of the cycle the pump to move the blood through the large and small circulation. In the case of diseases such as congestive heart failure, the heart loses its ability to pump adequate. This leads to congestion in the venous System and reduced blood flow in the periphery as well as the internal organs.
The arteries and veins
Blood vessels play a crucial role in the Regulation of blood pressure and blood flow. Atherosclerosis, a common disease of the arteries that leads to narrowing of the vessel lumen by Plaques. This increases the risk of myocardial infarction (due to occlusion of the coronary arteries) and stroke (due to occlusion of cerebral arteries).
Renal function and blood pressure regulation
The kidneys are closely associated with the circulatory system. They regulate the fluid and electrolyte balance, and produce hormones such as Renin, which is involved in the Renin‑Angiotensin‑aldosterone‑System (RAAS). In the case of chronic heart failure, it can lead to renal hypoperfusion leading to the activation of the RAAS and, therefore, the blood pressure further increases, a typical example of a pathological cycle.
Lung in the left chamber insufficiency
In the case of left ventricular heart failure, the blood in the pulmonary circulation, which can lead to pulmonary hypertension, and Edema of the lungs is jammed. Breathing becomes more difficult, and the gas exchange function of the alveoli is affected. These symptoms are as cardiac pulmonary oedema, known and are one of the acute complications of cardiovascular diseases.
The brain and the cerebral circulation
An impaired coronary circulation can also cause damage to the brain. Hypotension or arrhythmias may lead to an insufficient supply of oxygen (hypoxia), while atherosclerosis of the carotid arteries increases the risk of ischemic stroke. In the long term, persistent, may lead to the end of hypertension also to micro-vascular damage and cognitive limitations.
Liver and congestion of the liver
In the case of right-hearted heart failure, a back pressure in the venous System, which also relates to the inferior Vena cava and the liver. This leads to the development of a congestion of the liver (hepatomegaly with congestion), in the liver and functionally impaired is increased. It can
## Hypertensive heart and circulatory diseases ##
Hypertensive cardiovascular disease: causes, clinical picture and therapy approaches
Hypertension, also called high blood pressure is known, is one of the most important risk factors for heart and vascular diseases. In the case of a permanent increase in blood pressure (Systolic≥140 mmHg, Diastolic≥90 mmHg) forced the heart to pump against increased resistance. This leads to long-term structural and functional changes in the cardiovascular system.
Causes and risk factors
Primary (essential) hypertension, which occurs in about 90% of the cases that has no clear cause, however, the following factors play an important role:
genetic predisposition;
unhealthy diet (high salt content);
Overweight and obesity;
lack of physical activity;
chronic Stress;
Alcohol consumption and nicotine dependence.
Secondary hypertension can be on certain diseases of the back, such as:
Kidney disease;
endocrine disorders (e.g., hyperthyroidism, Cushing's syndrome);
Medication side effects.
Pathophysiological Development
Continuous load due to increased blood pressure leads to the following changes:
Left heart enlargement (hypertrophy of the left ventricle) of The heart muscle tissue is thickened, to the increased pressure. First of all, this is an adaptative response, but long-term it leads to the restriction of the function of the heart.
Atherosclerosis: The vascular walls lose their elasticity, harden and become narrow. This increases the risk of blood clots, heart attacks and strokes.
Kidney damage: the damage to the renal vessels, it can lead to impairment of renal function, which in turn increases the blood pressure (vicious circle).
Clinical Symptoms
Hypertensive heart disease often show up only in advanced stages. Possible symptoms are:
Headaches, especially in the morning;
Dizziness;
Blurred vision;
Chest pain (Angina pectoris);
Shortness of breath with exertion;
Edema of the legs.
Diagnostics
Comprehensive diagnostics includes:
regular blood pressure measurements over several days (Ambulatory blood pressure monitoring);
ECG for the detection of cardiac arrhythmias and signs of ventricular hypertrophy;
Echocardiography for the assessment of cardiac structure and function;
Laboratory Tests (Lipid Spectrum, Kidney Tests, Blood Sugar);
Ultrasound of the renal vessels and the carotid arteries for the evaluation of vascular changes.
Therapeutic Measures
The therapy is based on two main points: lifestyle changes and drug treatment.
Lifestyle changes:
Reduction of salt consumption (<5 g/day);
Weight loss in Obesity;
regular physical activity (150 minutes/week of moderate endurance training);
Waiver of nicotine and reduction of alcohol consumption;
Stress management techniques.
Drug Therapy:
ACE inhibitors or AT1‑receptor blockers (e.g., Lisinopril, Valsartan) for lowering blood pressure and heart protection;
Beta blocker (Metoprolol) on the reduction of heart rate and performance;
Calcium channel blocker (amlodipine) to vessel expansion;
Diuretics (hydrochlorothiazide) to the liquid reduction.
Forecast and prevention
With early diagnosis and consequent therapy of the progression of hypertensive cardiovascular disease significantly slow down. Regular medical check-UPS, especially in the Presence of risk factors, therefore, are of Central importance. The combination of a healthy way of life and adequate medication allows the majority of patients, a high quality of life over many years to maintain.
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## Pathophysiology of diseases of the cardiovascular System ##
Pathophysiology of diseases of the cardiovascular system: Deepen your Knowledge!
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